| Date | Location | Result | Â |
| Nov 27, 2010   | New Orleans, La.   | Tulane 3, Southern Miss 0 (25-16,25-17,25-16)   | Box score  |
| Nov 21, 2010   | Huntington, W.Va.   | Marshall 3, Southern Miss 0 (25-23,25-22,25-17)   | Box score  |
| Nov 19, 2010   | Greenville, N.C.   | Southern Miss 3, East Carolina 0 (26-24,25-21,25-16)   | Box score  |
| Nov 14, 2010   | Hattiesburg, Miss.   | Southern Miss 3, Memphis 1 (25-11,23-25,28-26,25-20)   | Box score  |
| Nov 12, 2010   | Hattiesburg, Miss.   | Southern Miss 3, UAB 0 (25-23,25-22,25-21)   | Box score  |
| Nov 07, 2010   | Orlando, Fla.   | UCF 3, Southern Miss 0 (25-17,25-22,25-18)   | Box score  |
| Nov 5, 2010   | El Paso, Texas   | Southern Miss 3, UTEP 0 (25-14,25-15,25-23)   | Box score  |
| Oct 31, 2010   | Birmingham, Ala.   | Southern Miss 3, UAB 1 (29-27,25-18,22-25,25-19)   | Box score  |
| Oct 29, 2010   | Memphis, Tenn.   | Southern Miss 3, Memphis 2 (25-21,20-25,23-25,25-20,15-8)   | Box score  |
| Oct 24, 2010   | Hattiesburg, Miss.   | Southern Miss 3, East Carolina 0 (25-15,25-16,25-21)   | Box score  |
| Oct 22, 2010   | Hattiesburg, Miss.   | Southern Miss 3, Marshall 2 (22-25,18-25,25-20,25-19,15-11)   | Box score  |
| Oct 20, 2010   | Hattiesburg, Miss.   | Southern Miss 3, Tulane 1 (25-17,23-25,25-19,25-14)   | Box score  |
| Oct 17, 2010   | Hattiesburg, Miss.   | Southern Miss 3, UTEP 0 (25-19,25-20,25-15)   | Box score  |
| Oct 15, 2010   | Hattiesburg, Miss.   | Southern Miss 3, UCF 2 (25-19,23-25,25-16,19-25,15-12)   | Box score  |
| Oct 10, 2010   | Houston, Texas   | Houston 3, Southern Miss 1 (25-20,18-25,25-20,25-23)   | Box score  |
| Oct 09, 2010   | Houston, Texas   | Houston 3, Southern Miss 1 (25-20,22-25,25-23,25-23)   | Box score  |
| Oct 03, 2010   | Dallas   | SMU 3, Southern Miss 2 (27-25,23-25,21-25,25-22,15-10)   | Box score  |
| Oct 01, 2010   | Hattiesburg, Miss.   | Tulsa 3, Southern Miss 0 (25-23,25-23,25-10)   | Box score  |
| Sep 25, 2010   | Hattiesburg, Miss.   | Southern Miss 3, Rice 1 (17-25,25-23,25-17,26-24)   | Box score  |
| Sep 24, 2010   | Hattiesburg, Miss.   | Rice 3, Southern Miss 1 (25-23,25-20,20-25,25-22)   | Box score  |
| Sep 15, 2010   | Hattiesburg, Miss.   | Southern Miss 3, Mississippi State 0 (25-18,25-16,25-18)   | Box score  |
| Sep 11, 2010   | Oxford, Miss.   | Southern Miss 3, Samford 0 (25-20,25-17,25-13)   | Box score  |
| Sep 10, 2010   | Oxford, Miss.   | Mississippi 3, Southern Miss 2 (22-25,25-23,25-21,22-25,17-15)   | Box score  |
| Sep 10, 2010   | Oxford, Miss.   | Southern Miss 3, Louisiana 1 (25-9,18-25,25-19,25-17)   | Box score  |
| Sep 05, 2010   | Murfreesboro, Tenn.   | Auburn 3, Southern Miss 0 (25-19,25-20,26-24)   | Box score  |
| Sep 04, 2010   | Murfreesboro, Tenn.   | Miami 3, Southern Miss 1 (26-24,25-15,22-25,25-23)   | Box score  |
| Sep 04, 2010   | Murfreesboro, Tenn.   | Middle Tennessee 3, Southern Miss 2 (25-21,25-16,23-25,23-25,15-10)   | Box score  |
| Sep 03, 2010   | Murfreesboro, Tenn.   | Southern Miss 3, GSU 2 (25-13,22-25,19-25,25-22,15-11)   | Box score  |
| Aug 28, 2010   | Hattiesburg, Miss.   | Southern Miss 3, Kennesaw State 0 (27-25,25-19,27-25)   | Box score  |
| Aug 27, 2010   | Hattiesburg, Miss.   | Southern Miss 3, Nicholls State 0 (25-14,25-13,25-18)   | Box score  |
| Aug 27, 2010   | Hattiesburg, Miss.   | Southern Miss 3, South Alabama 0 (25-12,25-15,25-15)   | Box score  |
