| Date | Location | Result | Â |
| Jun 6, 2010   | Auburn, Ala   | Auburn 17, Southern Miss 8   | Box score  |
| Jun 5, 2010   | Auburn, Ala.   | Southern Miss 19, Jacksonville St 6   | Box score  |
| Jun 4, 2010   | Auburn, Ala.   | Clemson 10, Southern Miss 1   | Box score  |
| May 29, 2010   | Houston   | Southern Miss 7, Rice 4   | Box score  |
| May 28, 2010   | Houston, Texas   | Southern Miss 10, Houston 6   | Box score  |
| May 27, 2010   | Houston   | East Carolina 8, Southern Miss 1   |
| May 26, 2010   | Houston, Texas   | Southern Miss 8, Memphis 2   | Box score  |
| May 22, 2010   | Hattiesburg, Miss   | Southern Miss 5, Memphis 3   | Box score  |
| May 21, 2010   | Hattiesburg, Miss   | Memphis 10, Southern Miss 8   | Box score  |
| May 20, 2010   | Hattiesburg, Miss.   | Southern Miss 9, Memphis 3   | Box score  |
| May 18, 2010   | Hattiesburg, Miss   | Mississippi State 16, Southern Miss 9   | Box score  |
| May 16, 2010   | Houston, Texas   | Rice 21, Southern Miss 14   | Box score  |
| May 15, 2010   | Houston, Texas   | Rice 10, Southern Miss 2   | Box score  |
| May 15, 2010   | Houston, Texas   | Southern Miss 11, Rice 10   | Box score  |
| May 9, 2010   | Hattiesburg, Miss   | Southern Miss 7, East Carolina 6   | Box score  |
| May 8, 2010   | Hattiesburg, Miss   | Southern Miss 8, East Carolina 2   | Box score  |
| May 7, 2010   | Hattiesburg, Miss.   | Southern Miss 14, East Carolina 4   | Box score  |
| May 05, 2010   | Pearl, Miss.   | Southern Miss 14, Mississippi State 3   | Box score  |
| May 2, 2010   | New Orleans, La.   | Southern Miss 13, Tulane 9   | Box score  |
| May 1, 2010   | New Orleans, La   | Southern Miss 4, Tulane 2   | Box score  |
| Apr 30, 2010   | New Orleans, La.   | Southern Miss 16, Tulane 2   | Box score  |
| Apr 28, 2010   | Hattiesburg, Miss.   | Southern Miss 15, South Alabama 5   | Box score  |
| Apr 25, 2010   | Hattiesburg, Miss   | Southern Miss 8, Houston 5   | Box score  |
| Apr 24, 2010   | Hattiesburg, Miss   | Southern Miss 13, Houston 4   | Box score  |
| Apr 23, 2010   | Hattiesburg, Miss   | Southern Miss 10, Houston 9   | Box score  |
| Apr 20, 2010   | Oxford, Miss.   | Ole Miss 7, Southern Miss 2   | Box score  |
| Apr 18, 2010   | Charleston, WV   | Marshall 6, Southern Miss 3   | Box score  |
| Apr 17, 2010   | Charleston, WV   | Marshall 6, Southern Miss 3   | Box score  |
| Apr 16, 2010   | Charleston, WV   | Southern Miss 16, Marshall 7   | Box score  |
| Apr 13, 2010   | New Orleans, La.   | Southern Miss 3, New Orleans 2   | Box score  |
| Apr 11, 2010   | Hattiesburg, Miss   | Central Florida 9, Southern Miss 8   | Box score  |
| Apr 10, 2010   | Hattiesburg, Miss   | Central Florida 11, Southern Miss 10   | Box score  |
| Apr 9, 2010   | Hattiesburg, Miss   | Central Florida 7, Southern Miss 3   | Box score  |
| Apr 7, 2010   | Metairie, La.   | LSU 6, Southern Miss 5   | Box score  |
| Apr 3, 2010   | Hattiesburg, Miss.   | Southern Miss 15, St. Mary's 7   | Box score  |
| Apr 2, 2010   | Hattiesburg, Miss.   | Southern Miss 4, St. Mary's 3   | Box score  |
| Apr 1, 2010   | Hattiesburg, Miss.   | St. Mary's 19, Southern Miss 11   | Box score  |
| Mar 30, 2010   | Mobile, Ala.   | South Alabama 14, Southern Miss 13   | Box score  |
| Mar 27, 2010   | Birmingham, Ala.   | Southern Miss 14, UAB 3   | Box score  |
| Mar 27, 2010   | Birmingham, Ala.   | UAB 13, Southern Miss 8   | Box score  |
| Mar 26, 2010   | Birmingham, Ala.   | UAB 4, Southern Miss 2   | Box score  |
| Mar 23, 2010   | Pearl, Miss.   | Ole Miss 11, Southern Miss 6   | Box score  |
| Mar 20, 2010   | Ruston, La.   | Southern Miss 15, La. Tech 7   | Box score  |
| Mar 19, 2010   | Ruston, La.   | La. Tech 4, Southern Miss 3   | Box score  |
| Mar 17, 2010   | Monroe, La.   | Southern Miss 8, La. Monroe 7   | Box score  |
| Mar 16, 2010   | Hattiesburg, Miss.   | Southern Miss 11, New Orleans 2   | Box score  |
| Mar 14, 2010   | Hattiesburg, Miss   | Southern Miss 13, Missouri State 4   | Box score  |
| Mar 13, 2010   | Hattiesburg, Miss   | Southern Miss 6, Missouri State 0   | Box score  |
| Mar 12, 2010   | Hattiesburg, Miss   | Southern Miss 4, Missouri State 3   | Box score  |
| Mar 07, 2010   | Lafayette, La.   | Louisiana- Lafayette 10, Southern Miss 6   | Box score  |
| Mar 06, 2010   | Lafayette, La.   | Southern Miss 6, Louisiana- Lafayette 1   | Box score  |
| Mar 05, 2010   | Lafayette, La.   | Southern Miss 4, Louisiana- Lafayette 0   | Box score  |
| Mar 3, 2010   | Hattiesburg, Miss.   | Southern Miss 14, La. Monroe 5   | Box score  |
| Feb 28, 2010   | Hattiesburg, Miss.   | LeMoyne 12, Southern Miss 11   | Box score  |
| Feb 27, 2010   | Hattiesburg, Miss   | Southern Miss 10, LeMoyne 3   | Box score  |
| Feb 26, 2010   | Hattiesburg, Miss.   | LeMoyne 6, Southern Miss 2   | Box score  |
| Feb 24, 2010   | Hattiesburg, Miss   | Southern Miss 20, Miss. Valley 2   | Box score  |
| Feb 21, 2010   | Hattiesburg, Miss.   | Northwestern St 7, Southern Miss 5   | Box score  |
| Feb 20, 2010   | Hattiesburg, Miss   | Southern Miss 7, Northwestern St 3   | Box score  |
| Feb 19, 2010   | Hattiesburg, Miss.   | Southern Miss 11, Northwestern St 0   | Box score  |
