| Date | Location | Result | Â |
| Dec 20, 2009   | New Orleans, LA   | Middle Tennessee 42, Southern Miss 32   | Box score  |
| Nov 28, 2009   | Greenville, N.C.   | East Carolina 25, Southern Miss 20   | Box score  |
| Nov 21, 2009   | Hattiesburg, Miss.   | Southern Miss 44, Tulsa 34   | Box score  |
| Nov 14, 2009   | Huntington, WV   | Southern Miss 27, Marshall 20   | Box score  |
| Oct 31, 2009   | Houston, Texas   | Houston 50, Southern Miss 43   | Box score  |
| Oct 24, 2009   | Hattiesburg, Miss.   | Southern Miss 43, Tulane 6   | Box score  |
| Oct 17, 2009   | Hattiesburg, Miss.   | Southern Miss 36, Memphis 16   | Box score  |
| Oct 10, 2009   | LOUISVILLE, KY   | LOUISVILLE 25, Southern Miss 23   | Box score  |
| Oct 01, 2009   | Birmingham, Ala.   | UAB 30, Southern Miss 17   | Box score  |
| Sep 26, 2009   | Lawrence, Kan.   | Kansas 35, Southern Miss 28   | Box score  |
| Sep 19, 2009   | Hattiesburg, Miss.   | Southern Miss 37, Virginia 34   | Box score  |
| Sep 12, 2009   | Hattiesburg, Miss.   | Southern Miss 26, UCF 19   | Box score  |
| Sep 05, 2009   | Hattiesburg, Miss.   | Southern Miss 52, Alcorn State 0   | Box score  |
